I started to investigate the general issue where soase would crash on startup if certain apps were running. My game crashed on startup when I have Blackbox for Windows running (bb4win). I used filemon.exe from www.sysinternals.com (popular free IT tool website), and found some rather strange things that Sins is doing. Alot of it is junk but you can filter out things.  Maybe useful for some people.

Edit.  There was a post of some specific stuff I found, but it didn't seem useful after looking through more.