The title and subtitle basically state the information.
I have a new monitor installed as of today, which supports 1080i and 720p resolutions by television standards. I have it running at 1680x1050 at the moment. When I loaded up Sins to see how it would look, it was in it's window of 1028x764 (pardon if I misremember numbers) that I had it running on the old 1280x1024 monitor. When I went to adjust the resolution, the 'apply' button never lit up. It wouldn't let me change, or even leave windowed mode!
As note - I was able to apply and change settings under the 'effects' tab.
Entrenchment beta is installed, so this may be an issue related to that.
My video card is an nVidia 8600 GT w/ 512 MB DDR2. My CPU is an Intel Wolfdale E8400. (45nm @ 3.0gHz)