then I'd say find where the two strong empires' fronts meet, and hit one of each of their planets. the AI will always break off any attack to rescue their planets, as long as they have some form of sizeable force. I would suggest pitting the AIs against each other with bounty. (i.e. place a decent sum on each, to start a bidding war between them.
another idea is to use an extremely strong counterattack. as soon as you fight off an attack, follow that fleet until you have destroyed a sizable portion, including the caps. then race back to your territory, in case you have to defend against another attack. the counterattack will buy you plenty of time, and will allow you to deal with them one at a time. if you can, narrow it down to one chokepoint each, and stay on the offensive. the way the AI is set up, it will not try a diversionary attck to pull your forces away, so if you are attacking somewhere, they won't attack you.