On both Vista and Windows 7 64 bit the game crashes. No mods. Windows 7 is a clean install and while I know it's in beta, it's fairly similar to Vista.

I've found that it only crashes on me, however, if my graphics settings are turned to max. I just came from a game where I had everything set to low with no crashes whatsoever. I didn't have this issue with vanilla sins, but I did have it when using Danman's 7 Deadly Sins mod which added a lot of new graphical elements. If I didn't run the game on low it would dump.

The crashing on high only started again when I installed entrenchment. Again, clean install, no mods.

My system:

Intel q6600

2gb DDR2

BFG 8800Ultra

Running Windows 7 Ultimate 64.

I don't have crashing issues with any other game on my system with settings cranked. The only game I continually have crashing issues due to high settings is Sins + Entrench.

Hoping this might help?