I'm having the same issue.
I just bought the store version today. When I insert the disc, it brings up the autorun screen. I choose install, and it starts the installation wizard. After I agree to the license agreement and pick an install directory, it loads up the installer than immediately quits with an "Error" box. It kicks me back to another screen and says that I had a "fatal error during installation."
I also had the demo installed, so I deleted the demo. I'm still having the same install problem though. I've tried custom directories and the default directory. I've also tried taking off all of my stardock directories. I still can't get this to work. Any suggestions? Thanks.