Im using 180.48 for 64-bit Vista but I just noticed that the new 181.20 are out just before I came on here. So will give those a try and see if I have to keep disabling SLI whenever I want to play Sins. Its not that big of an issue. Only thing that annoys me is everytime I switch between SLI and non SLI my icons on the desktop get shuffled around and I gotta move everthing back.
I can play Sins maxed out on 1 8800GTX so I guess 2 isnt of much benefit in SLI anyway. The real problem happens with the mega mines, you let a game go on to long and its almost unplayable even with an Q6600 overclocked to 3.2 gigahertz and 4 gig of memory.