If you're talking about AI, 3-4 hangars, 3-4 repair bays, and the rest beam turrets. Fill the hangars with fighters. Put your beam turrets in front, with the repair bays and hangars farther back so they don't get primaried by everything.
If you've got Entrenchment, make sure to research the hangars' shield ability that gives everything around it 750 shields, and the Synergy tech for turrets which also gives them shields and a damage boost for each nearby turret (up to +1000 shields and 50% damage). Then throw in a Transcendia, close enough to the front but surrounded by the beam turrets and research its Meteor Storm and Mass Disorient abilities, and the AI will have a very hard time breaking it.