I've had this happen before...I don't have any files to give you but I was personally able to get this problem to manifest itself many times...
I usually do a clean reinstall of my OS every couple of months...after drivers and my internet browser, the first thing I'd usually install would be Impulse and then Sins (Diplomacy and Entrenchment as separate downloads, not trinity) so it could download while I'd be updating other things...
It would turn out that I would always be able to run Sins fine the first time, but after that initial launch, the game would always crash upon start-up...clearing everything in AppData did not help, and so I'd always have to reinstall the game in order to play it again...after reinstalling the game, I'd never see the problem again...
This has happened every time I've reinstalled windows 7 (about 5-6 times) except the most recent time, where I installed impulse and sins after installing MS Office and a few other programs...
I assumed it was because I had some bad sector on my hardrive or something, and Sins (since it was always installed first ) just kept being put there after each time the OS was re-installed...strangely, no such bad sector has ever been detected and no other program has had this program, so maybe it was a different issue...
I know this is not rebellion or trinity, but it is diplomacy and it did occur consistently multiple times under the same conditions...sorry if this isn't particularly useful but it's all I got....