I played the M&M games more than any other rpg as a kid... more than Baldur's Gate, more than Ultima.
If they screw this up it will make me very sad.
Different company, of course, so screwing it up is certainly possible. That said, Caneghem's flagship series was getting a bit creaky towards the end, recycling ideas he'd had as far back as M&M II, if not M&M I. Great series, though, and if they do it up right, with decent improvements very much in the spirit of the original, I'm sure it could sell.
Parenthetically, I wish Caneghem hadn't sold New World Computing to 3DO. It was Tripp's company, one of the founders of EA, which meant generous buy-in terms, and a ruthless control of product that was aimed solely at creating a massive cash cow to fund Tripp's other failing titles. There were many spin-offs at the time that were completely unworthy of the M&M series.