Well, there are very few abilities you'd actually want to do this on anyway, but for the few it would affect it obviously is a huge drawback being unable to do it quickly...the main ones I can think of are the self-repair on the skirmishers and enforcers as well as the kanrak/sentinel abilities...martyrdom and repulsion might also be worth looking into...the last group would be anti-SC abilities like flak burst, TK push, and JW, but tabbing is somewhat viable with those depending on what caps you have and what order they appear in the empire tree...
You could mod the ability files so that the skirmisher/enforcer self-repair abilities autocast at a higher hull %, that would be a fairly simple mod, only editing 2 files...idk about charged missiles, might not be able to tweak those...were there any other abilities you were interested in?