Hmm sounds strange when it is ingame and not while you are loading the mod from the mod options. Well, what are your computer specs? Wich version of sins do you use now and what mods? And do you know how to run the dev.exe?

• Core i7 @ 2.7GHz
• 12 gigs of RAM
• NVIDIA GeForce GTX 285
• DirectX 10
• Windows Vista 64-bit

I am using the Entrenchment expansion. The mods are: Sins of the 13th Tribe, Sins of a Galactic Empire, Star Wars Requiem, and a mod to raise the fleet capacity and cap ship capacity by a small amount. I have all of the latest updates for the actual games, and the mods as well. If the issue stems from the graphics settings being on Highest, then I have another problem on my hands. The problem is that when I go to change the settings, I change all of the settings to just High, everything seems fine and dandy. However, when I restart the game to make sure the settings have been saved, they have all reverted back to their original Highest settings. And finally, when I try to use the dev.exe, an error message occurs saying that "fmod.dll has not been found" and then the game stops working.

What dev.exe are you using?  the .dll usually means that the dev.exe doesn't work with your version of sins. The current verion of the dev.exe is found in your install folder. have ypu tried and remove the folder named pipeline effects in the mods folder. Sometimes it can cause errors for certain people (I am one of those people).