I think we're likely to integrate ourselves into the substrate long before we start sending meat-versions of ourselves to other planets.
That is, I think that the time will come when we incorporate all that is "us" into what we would call the digital leaving behind the organic forms. Then we'll send out machines that can convert other planets into the same substrate material to other planets.
I don't think there's a future in transporting meat around the galaxy.
Yeah, I think I said as much earlier. Though I'm not convinced that this 'transcendence' will require technology, but it certainly could go that way.
The question will be, will it be easier to plumb the depths of the human mind or to plumb the depths of the galaxy (universe eventually).