just went on to continue my game from yesterday, which finished abruptly with a desktop crash, as i attacked heavily defended TEC Rebel planet. So i loaded a save today (created shortly before the jump to the enemy world), jumped in again, met the enemy fleet consisting of up to 10 capships, Ragnarov and shitload of strike craft, zoomed in and out, game would crash again. So rinse and repeat, loaded the game, loaded the save, jumped in, the battle started, crash to desktop...

Was planning already to send the save file to StarClad, but decided to drop my GPU overclock first, and it helped! I mean i lost my fleet and my titan in the end, but there was no crash, but choppiness at the most intensive moments of battle, when most of the ships were still alive...

I am going to give it another try now, to see, if this was not premature, but i would be surprised, if it crashed.  Does anyone know, if Sins supports multiGPU/SLI setups? I could turn it on to see, if it makes the battle less choppy (and what it does again to stability, though the card should be stable with both GPUs running on default clocks).

TL,DR: If you experience unexpected desktop crashes during intense battles and have your HW overclocked, drop the overclock down to see, if it helps. It did for me. The fact, other games/apps are stable with your overclock is irrelevant, as i can play Call of Duty with overclock and no hassle as well. Clearly though, Sins can be more demanding.